SAV1 Mouse Monoclonal Antibody [Clone ID: LBI7C7]

• Background:

  WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1) -associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug

• Synonyms:

  SAV; WW45; WWP4

• Gene Name:

  Salvador family WW domain containing protein 1

• Gene ID:

  60485

• UniProt:

  Q9H4B6

• Conjugation:

  Unconjugated

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  SAV1

• Overview:

  SAV1 mouse monoclonal antibody, clone LBI7C7

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=60485

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H4B6