SAPK4 (MAPK13) Mouse Monoclonal Antibody [Clone ID: LBI12C3]

• Background:

  The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase. [provided by RefSeq, Jul 2008]

• Synonyms:

  MAPK-13; MAPK 13; p38delta; PRKM13; SAPK4

• Gene Name:

  Mitogen-activated protein kinase 13

• Gene ID:

  5603

• UniProt:

  O15264

• Conjugation:

  Unconjugated

• Related Pathways:

  Amyotrophic lateral sclerosis (ALS), Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, GnRH signaling pathway, Leukocyte transendothelial migration, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway

• Field of Research:

  Amyotrophic lateral sclerosis (ALS), Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, GnRH signaling pathway, Leukocyte transendothelial migration, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000, IHC 1:150, IF 1:100

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Protein Kinase

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  MAPK13

• Overview:

  MAPK13 (SAPK4) mouse monoclonal antibody, clone LBI12C3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5603

• Uniprot URL:

  https://www.uniprot.org/uniprot/O15264