PMVK Mouse Monoclonal Antibody [Clone ID: LBI1C12]

• Background:

  This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011]

• Synonyms:

  HUMPMKI; PMK; PMKA; PMKASE; POROK1

• Gene Name:

  Phosphomevalonate kinase

• Gene ID:

  10654

• UniProt:

  Q15126

• Conjugation:

  Unconjugated

• Related Pathways:

  Metabolic pathways, Terpenoid backbone biosynthesis

• Field of Research:

  Metabolic pathways, Terpenoid backbone biosynthesis

• Concentration:

  0.6 mg/ml

• Dilution:

  WB 1:2000, IF 1:100

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PMVK

• Overview:

  PMVK mouse monoclonal antibody, clone LBI1C12

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=10654

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15126