LNK (SH2B3) Mouse Monoclonal Antibody [Clone ID: LBI2C9]

• Background:

  This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

• Synonyms:

  IDDM20; LNK

• Gene Name:

  SH2B adaptor protein 3

• Gene ID:

  10019

• UniProt:

  Q9UQQ2

• Conjugation:

  Unconjugated

• Related Pathways:

  Neurotrophin signaling pathway

• Field of Research:

  Neurotrophin signaling pathway

• Concentration:

  0.8 mg/ml

• Dilution:

  WB 1:500, IF 1:100, FLOW 1:100

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  SH2B3

• Overview:

  SH2B3 (LNK) mouse monoclonal antibody, clone LBI2C9

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=10019

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UQQ2