(DANRE) srrt Antibody (C-Term) [APR33255G]

• Synonyms:

  Serrate RNA effector molecule homolog, Arsenite-resistance protein 2, srrt, ars2

• Gene Name:

  Srrt

• Gene ID:

  192311

• UniProt:

  Q66I22

• Chromosomal Location:

  Nucleus, nucleoplasm. Cytoplasm. Note=Predominantly nuclear. Shuttles between the nucleus and the cytoplasm (By similarity) .

• Applications:

  WB

• Dilution:

  WB--1:2000

• Function:

  Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity) . Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity) .

• Molecular Weight:

  103274

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (DANRE) srrt Antibody (C-Term) [APR33255G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=192311

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q66I22