H1FOO Antibody (Center) [APR31501G]

• Background:

  Tissue Location: Oocyte-specific..

• Synonyms:

  Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1, osH1, H1FOO, H1OO, OSH1

• Gene Name:

  HGNC:18463

• Gene ID:

  132243

• UniProt:

  Q8IZA3

• Chromosomal Location:

  Cytoplasm. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00837}. Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837}

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity) .

• Molecular Weight:

  35813

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality H1FOO Antibody (Center) [APR31501G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=132243

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8IZA3