H1oo (H1FOO) (NM_153833) Human Recombinant Protein

• Background:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes. [provided by RefSeq, Oct 2015]

• Synonyms:

  H1.8; H1FOO; H1oo; osH1

• Gene ID:

  132243

• UniProt:

  Q8IZA3

• Accession Number mRNA:

  NM_153833

• Chromosomal Location:

  3q22.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  35.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  H1FOO

• Species:

  Human

• Protein ID:

  NP_722575

• Overview:

  Recombinant protein of human H1 histone family, member O, oocyte-specific (H1FOO)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/132243

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8IZA3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_153833

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_722575