TRIM26 Antibody (N-term) [APR31460G]

• Synonyms:

  Tripartite motif-containing protein 26, Acid finger protein, AFP, RING finger protein 95, Zinc finger protein 173, TRIM26, RNF95, ZNF173

• Gene Name:

  TRIM26

• Gene ID:

  7726

• UniProt:

  Q12899

• Chromosomal Location:

  Cytoplasm. Nucleus. Note=Viral infection mediates TRIM26 nuclear translocation.

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs) . Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.

• Molecular Weight:

  62166

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRIM26 Antibody (N-term) [APR31460G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=7726

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q12899