Trim26 (NM_001025599) Mouse Recombinant Protein

• Background:

  E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs) . Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AI462198; Zfp173; Zfp1736

• Gene ID:

  22670

• UniProt:

  Q99PN3

• Accession Number mRNA:

  NM_001025599

• Chromosomal Location:

  17 19.16 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  62.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Trim26

• Species:

  Mouse

• Protein ID:

  NP_001020770

• Overview:

  Purified recombinant protein of Mouse tripartite motif-containing 26 (Trim26), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/22670

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99PN3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001025599

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001020770