ATAD2 Antibody (N-term) [APR31065G]

• Background:

  Tissue Location: Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.

• Synonyms:

  ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ANCCA, ATAD2

• Gene Name:

  ATAD2

• Gene ID:

  29028

• UniProt:

  Q6PL18

• Chromosomal Location:

  Nucleus.

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

• Molecular Weight:

  158554

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATAD2 Antibody (N-term) [APR31065G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=29028

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6PL18