RAP2A Antibody (N-Term) [ApR04914G]

• Synonyms:

  Ras-related protein Rap-2a, RbBP-30, RAP2A

• Gene Name:

  RAP2A

• Gene ID:

  5911

• UniProt:

  P10114

• Chromosomal Location:

  Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. Note=May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995) . Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443) .

• Applications:

  WB

• Dilution:

  WB--1:1000

• Function:

  Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

• Molecular Weight:

  20615

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAP2A Antibody (N-Term) [ApR04914G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5911

• Uniprot URL:

  https://www.uniprot.org/uniprot/P10114