Anti Human CD38 mAb, Carrier-free (BSA/Glycerol-free)

• Background:

  The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

• Synonyms:

  ADPRC1; cADPR1; ADPRC 1

• Gene Name:

  CD38, Homo sapiens (Human)

• UniProt:

  P28907

• Conjugation:

  Unconjugated

• Applications:

  Functional Assays

• Form:

  Liquid

• Buffer:

  PBS, pH7.4

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  CD38

• Overview:

  A monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38 , a protein highly expressed on hematological malignant cells, including those in multiple myeloma (MM) . We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.

• Uniprot URL:

  https://www.uniprot.org/uniprotkb/P28907/entry

• Gene Name URL:

  https://www.ncbi.nlm.nih.gov/gene/952