MPIF-1/CCL23 Protein, Human, Recombinant

• Background:

  CCL23, also known as MIP 3, is a small cytokine which belongs to the CC chemokine family. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL23 is predominantly expressed in lung and liver tissue, but also can be detected in bone marrow and placenta. It displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. CCL23 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.

• Synonyms:

  CCL23 Protein, Human; CK-BETA-8 Protein, Human; Ckb-8 Protein, Human; Ckb-8-1 Protein, Human; CKb8 Protein, Human; hmrp-2a Protein, Human; MIP-3 Protein, Human; MIP3 Protein, Human; MPIF-1 Protein, Human; MPIF1 Protein, Human; SCYA23 Protein, Human

• Gene Name:

  Chemokine (C-C motif) ligand 23

• Expression System:

  E. coli

• Tag:

  No tag

• Endotoxin:

  Please contact us for more information.

• Purity:

  > 95 % as determined by SDS-PAGE.

• Activity:

  At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.

• Form:

  Lyophilized

• Buffer:

  Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

• Function:

  Cytokine Proteins, Growth Factor proteins, Biological Target proteins

• Molecular Weight:

  The recombinant human CCL23 consists of 99 amino acids and predicts a molecular mass of 11.4 KDa. It migrates as an approximately 18 KDa band in SDS-PAGE under reducing conditions.

• Storage Conditions:

  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CCL23

• Species:

  Human

• Protein ID:

  AAB51134.1

• Overview:

  A DNA sequence encoding the human CCL23 (AAB51134.1) (Arg22-Asn120) was expressed.

• AA Sequence:

  Arg22-Asn120

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/protein/AAB51134.1