CD32B/Fcgr2b Protein, Human, Recombinant (ECD, His Tag)

• Synonyms:

  CD32 Protein, Human; CD32A Protein, Human; CD32B Protein, Human; CDw32 Protein, Human; Fc gamma RII Protein, Human; Fc gamma RIIB Protein, Human; FCG2 Protein, Human; FcGR Protein, Human; FCGR2 Protein, Human; FCGR21 Protein, Human; FCGR2A Protein, Human; IGFR2 Protein, Human

• Gene Name:

  Fc fragment of IgG, low affinity IIb, receptor (CD32)

• Expression System:

  HEK293 Cells

• Tag:

  C-His

• Field of Research:

  Fc Receptors ITIM/ITAM Immunoreceptors and Related Molecules

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by SDS-PAGE.

• Activity:

  Measured by its ability to bind biotinylated human IgG2 (Cat: 13504-HNAH) in functional ELISA.

• Form:

  Lyophilized

• Buffer:

  Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

• Function:

  CD Molecule proteins, Receptor Proteins, Fc receptor proteins, Immunotherapy proteins

• Molecular Weight:

  The recombinant mature human CD32b consists of 183 amino acids after proteolytic removal of the signal peptide and predicts a molecular mass of 20.8 kDa. By SDS-PAGE under reducing conditions, it migrates as an approximately 25-30 kDa protein due to glycosylation.

• Storage Conditions:

  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FCGR2B

• Species:

  Human

• Protein ID:

  NP_001002274.1

• Overview:

  A DNA sequence encoding the extracellular domain (Ala 46-Pro 217) of mature human CD32b (NP_001002274.1) protein was expressed with a N-terminal signal peptide and a C-terminal polyhistidine tag.

• AA Sequence:

  Ala46-Pro217

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/protein/NP_001002274.1