CD32B (FCGR2B) (NM_001002275) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE) . Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

• Synonyms:

  CD32; CD32B; FCG2; FCGR2; FCGR2C; FcRII-c; IGFR2

• Gene ID:

  2213

• UniProt:

  P31994

• Accession Number mRNA:

  NM_001002275

• Chromosomal Location:

  1q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus

• Field of Research:

  B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  ES Cell Differentiation/IPS, Transmembrane

• Molecular Weight:

  33.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FCGR2B

• Species:

  Human

• Protein ID:

  NP_001002275

• Overview:

  Recombinant protein of human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2213

• Uniprot URL:

  https://www.uniprot.org/uniprot/P31994

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001002275

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001002275