TP53 Antibody - C-terminal region: FITC (AVARP02055_T100-FITC)

• Gene Aliases:

  P53, BCC7, LFS1, BMFS5, TRP53

• Gene ID:

  7157

• Swiss Prot:

  P04637

• Accession Number:

  NP_000537

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Horse

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human TP53

• Target:

  TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  IHC, WB

• Sample Type:

  TP53 is strongly supported by BioGPS gene expression data to be expressed in DU145

• Concentration:

  0.5 mg/mL

• Homology:

  Horse: 93%; Human: 100%; Rat: 92%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  44kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  393

• NCBI Gene Symbol:

  TP53

• Protein Name:

  Cellular tumor antigen p53

• Nucleotide Accession Number:

  NM_000546