ALG10B Antibody - middle region: HRP (ARP67353_P050-HRP)

• Gene Aliases:

  KCR1, ALG10

• Gene ID:

  144245

• Swiss Prot:

  Q5I7T1

• Accession Number:

  NP_001013642

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Dog, Horse, Pig

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of Human ALG10B

• Target:

  ALG10B is a putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. ALG10B transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc (2) -PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.

• Partner Proteins:

  UBC; KCNH2

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Dog: 87%; Horse: 80%; Human: 100%; Pig: 87%; Rat: 80%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  55kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  473

• NCBI Gene Symbol:

  ALG10B

• Protein Name:

  Putative Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase

• Nucleotide Accession Number:

  NM_001013620