BRMS1 Antibody - C-terminal region: Biotin (ARP63978_P050-Biotin)

• Gene Name:

  Breast cancer metastasis suppressor 1

• Gene Aliases:

  DKFZp564A063

• Gene ID:

  25855

• Swiss Prot:

  G5E9I4

• Accession Number:

  NP_001020128

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep

• Target:

  This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC) . The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

• Partner Proteins:

  CEP70; NMI; HDAC2; HDAC1; SIN3A; APP; BRMS1L; ING1; HDAC6; HDAC4; TAF1; SMARCE1; SMTN; ARID4A; KPNA5; HSP90AA1; HSPA4; HDAC5; SUDS3; DNAJB6; UBC; SAP25; RELA; NFKB1; HDAC3; LRIF1; RBP1; PFDN5; DNAJB1; SAP30; RBBP4; RBBP7; GOLGB1; EEF1A1

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  BRMS1 is supported by BioGPS gene expression data to be expressed in 721_B

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%; Sheep: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  34kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  290

• NCBI Gene Symbol:

  BRMS1

• Protein Name:

  Breast cancer metastasis suppressor 1, isoform CRA_c EMBL EAW74515.1

• Nucleotide Accession Number:

  NM_001024957