CDH1 Antibody - middle region: Biotin (ARP59265_P050-Biotin)

• Gene Name:

  Cadherin 1, type 1, E-cadherin (epithelial)

• Gene Aliases:

  UVO, CDHE, ECAD, LCAM, Arc-1, BCDS1, CD324

• Gene ID:

  999

• Swiss Prot:

  P12830

• Accession Number:

  NP_004351

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human CDH1

• Target:

  Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

• Partner Proteins:

  UBC; MDM2; UCHL3; CDC27; PTEN; CTNNB1; PIP5K1C; CTNND1; CBLL1; RNF2; GMNN; LMNA; KRT18; KRT9; KRT8; KRT1; IGHA1; HSPD1; HSP90AA1; HSPA9; HSPA8; HSPA5; GBAS; CTNNA1; CRYAB; CFTR; C1QBP; ACTN4; ACADVL; ANP32B; NIPSNAP1; XRCC5; TGM2; SKP2; SET; RAD17; POLR2E

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 93%; Dog: 100%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 92%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  80kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  882

• NCBI Gene Symbol:

  CDH1

• Protein Name:

  Cadherin-1

• Nucleotide Accession Number:

  NM_004360