TRPC3 Antibody - N-terminal region: HRP (ARP58715_P050-HRP)

• Gene Name:

  Transient receptor potential cation channel, subfamily C, member 3

• Gene Aliases:

  TRP3, SCA41

• Gene ID:

  7222

• Swiss Prot:

  Q13507

• Accession Number:

  NP_003296

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the n terminal region of human TRPC3

• Target:

  TRPC3 is thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. TRPC3 is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. TRPC3 may also be activated by internal calcium store depletion.

• Partner Proteins:

  STX3; TRPC1; PRKG1; ORAI1; PLCB1; PLCB2; TRPC6; NAPA; PLCB3; FKBP1A; VAMP2; SLC8A1; PRKCA; PLCG1; ITPR3; ITPR1; MX1; GNA11; CALM1; TRPC7; TRPC3; TRPC5; TRPC4

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  97kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  848

• NCBI Gene Symbol:

  TRPC3

• Protein Name:

  Short transient receptor potential channel 3

• Nucleotide Accession Number:

  NM_003305