MED7 Antibody - middle region: FITC (ARP57925_P050-FITC)

• Gene Name:

  Mediator complex subunit 7

• Gene Aliases:

  ARC34, CRSP9, CRSP33

• Gene ID:

  9443

• Swiss Prot:

  O43513

• Accession Number:

  NP_004261

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human MED7

• Target:

  The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.

• Partner Proteins:

  HAUS1; CDK8; CDK19; MED13; MED19; MED26; EPAS1; MED6; UBE2I; UL48; SUMO2; UBC; CTDP1; MED10; MED25; MED15; MED14; VDR; SREBF1; RELA; PARP1; ZSCAN1; TRIM15; RHOXF2; PCBD2; MED31; TRIM29; RBFOX2; IKBKG; LZTR1; PML; MED9; MED8; HGS; MED1; HNF4A; ESR2; ESR1

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB, CHIP

• Purification:

  Affinity Purified

• Sample Type:

  MED7 is supported by BioGPS gene expression data to be expressed in Jurkat

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  27kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  233

• NCBI Gene Symbol:

  MED7

• Protein Name:

  Mediator of RNA polymerase II transcription subunit 7

• Nucleotide Accession Number:

  NM_004270