HLA-DQA2 Antibody - N-terminal region: HRP (ARP49464_P050-HRP)

• Gene Name:

  Major histocompatibility complex, class II, DQ alpha 2

• Gene Aliases:

  HLA-DCA, HLA-DXA, HLADQA2, DC-alpha, DX-ALPHA

• Gene ID:

  3118

• Swiss Prot:

  P01906

• Accession Number:

  NP_064440

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Goat, Rabbit, Sheep

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human HLA-DQA2

• Target:

  This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.

• Partner Proteins:

  UBC; HLA-DQB1; CD4; INS

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  HLA-DQA2 is supported by BioGPS gene expression data to be expressed in 721_B

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Goat: 100%; Human: 100%; Mouse: 85%; Rabbit: 86%; Rat: 86%; Sheep: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  28kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  255

• NCBI Gene Symbol:

  HLA-DQA2

• Protein Name:

  HLA class II histocompatibility antigen, DQ alpha 2 chain

• Nucleotide Accession Number:

  NM_020056