HLA-DQA2 antibody - middle region (ARP49465_P050)

• Gene Name:

  Major histocompatibility complex, class II, DQ alpha 2

• Gene Aliases:

  HLA-DCA, HLA-DXA, HLADQA2, DC-alpha, DX-ALPHA

• Gene ID:

  3118

• Swiss Prot:

  P01906

• Accession Number:

  NP_064440

• Reactivity:

  Human, Mouse, Cow, Goat, Horse, Pig, Rabbit, Sheep

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human HLA-DQA2

• Target:

  This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.

• Partner Proteins:

  UBC; HLA-DQB1; CD4; INS

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  LPMFSKFISFDPQSALRNMAVGKHTLEFMMRQSNSTAATNEVPEVTVFSK

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 86%; Goat: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Sheep: 86%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  28kDa

• Protein Length:

  255

• NCBI Gene Symbol:

  HLA-DQA2

• Host or Source:

  Rabbit

• Protein Name:

  HLA class II histocompatibility antigen, DQ alpha 2 chain

• Gene Name URL:

  HLA-DQA2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_020056