FBXO7 Antibody - middle region : FITC (ARP43128_P050-FITC)

• Gene Name:

  F-box protein 7

• Gene Aliases:

  FBX, FBX7, PKPS, FBX07, PARK15

• Gene ID:

  25793

• Swiss Prot:

  Q9Y3I1

• Accession Number:

  NP_036311

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human FBXO7

• Target:

  FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

• Partner Proteins:

  PSME3; PSMF1; PSMA3; SKP1; TRAF2; MAGED1; SHFM1; PINK1; PARK2; SEC24C; NEDD8; UBC; COPS5; COPS6; CUL1; BIRC2; RBBP6; XPO1; DLGAP5; ELF4; BIRC3; CDK6; UBE2D2; CDC34

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  IP, WB

• Purification:

  Affinity Purified

• Sample Type:

  FBXO7 is supported by BioGPS gene expression data to be expressed in MCF7

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 83%; Horse: 92%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 83%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  58kDa

• References & Citations:

  Chang, Y.F., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1022-1026

• Shipping Conditions:

  Wet Ice

• Protein Length:

  522

• NCBI Gene Symbol:

  FBXO7

• NCBI GB Accession Number:

  FBXO7

• Host or Source:

  Rabbit

• Protein Name:

  F-box only protein 7

• Nucleotide Accession Number:

  NM_012179

• Peptide Sequence:

  PGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDG