Hsd17b11 Antibody - middle region: HRP (ARP40842_P050-HRP)

• Gene Name:

  Hydroxysteroid (17-beta) dehydrogenase 11

• Gene Aliases:

  Pa, Dhr, SDR2, retS, Dhrs8, Pan1b, retSDR2

• Gene ID:

  114664

• Swiss Prot:

  Q9EQ06

• Accession Number:

  NP_444492

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

• Target:

  Hsd17b11 can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. Hsd17b11 may act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. It has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.

• Partner Proteins:

  Eed

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  33kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  298

• NCBI Gene Symbol:

  HSD17B11

• Protein Name:

  Estradiol 17-beta-dehydrogenase 11

• Nucleotide Accession Number:

  NM_053262