SYNCRIP Antibody - N-terminal region: HRP (ARP40640_T100-HRP)

• Gene Name:

  Synaptotagmin binding, cytoplasmic RNA interacting protein

• Gene Aliases:

  PP68, NSAP1, GRYRBP, HNRNPQ, HNRPQ1, GRY-RBP, hnRNP-Q

• Gene ID:

  10492

• Swiss Prot:

  O60506

• Accession Number:

  NP_006363

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human SYNCRIP

• Target:

  Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. SYNCRIP may be involved in translationally coupled mRNA turnover. It implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. It interacts in vitro preferentially with poly (A) and poly (U) RNA sequences.

• Partner Proteins:

  FUS; PRMT8; UBC; SPRTN; SUMO2; SUMO3; STAU1; MDM2; RPA3; RPA2; RPA1; RNF2; EED; rev; GNB2L1; IQGAP1; RPS21; RPL24; RPL23A; PSMD7; RPSA; IARS; PRMT1; HNRNPU; FKBP3; MAP1S; C14orf166; RPS27L; NELFB; PARK2; FBXO6; TARDBP; CSF2; CD81; IGSF8; HMGA2; ICAM1; HMG

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  69kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  623

• NCBI Gene Symbol:

  SYNCRIP

• Protein Name:

  Heterogeneous nuclear ribonucleoprotein Q

• Nucleotide Accession Number:

  NM_006372