NOVA1 Antibody - C-terminal region: HRP (ARP40397_P050-HRP)

• Gene Name:

  Neuro-oncological ventral antigen 1

• Gene Aliases:

  Nova-1

• Gene ID:

  4857

• Swiss Prot:

  A8K603

• Accession Number:

  NP_002506

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human NOVA1

• Target:

  NOVA1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer.This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.

• Partner Proteins:

  SRPK1; APP; PCBP1; RPP14; NOVA1; SMARCC2

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  52kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  507

• NCBI Gene Symbol:

  NOVA1

• Protein Name:

  CDNA FLJ75870, highly similar to Homo sapiens neuro-oncological ventral antigen 1 (NOVA1), transcript variant 1, mRNA EMBL BAF84157.1

• Nucleotide Accession Number:

  NM_002515