TrkA-IN-3
CAT:
804-HY-151948-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TrkA-IN-3
- CAS Number: 3026111-73-6
- UNSPSC Description: TrkA-IN-3 is a potent, subselective and allosteric TrkA inhibitor, with an IC50 of 22.4 nM. TrkA-IN-3 shows more than 8000-fold selectivity for TrkA over TrkB and TrkC. TrkA-IN-3 can be used for the research of pain[1].
- Target Antigen: Trk Receptor
- Type: Reference compound
- Related Pathways: Neuronal Signaling;Protein Tyrosine Kinase/RTK
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/trka-in-3.html
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: CN1C=CC(C2=CC(C(NC3=CC(C(O)=O)=CN=C3C4=CC=CC=C4)=O)=CC=C2C(F)(F)F)=N1
- Molecular Weight: 466.41
- References & Citations: [1]Tang S, et, al. Design, development and evaluation of a prodrug-type TrkA-selective inhibitor with antinociceptive effects in vivo. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114901.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported