POU3F3 Antibody - N-terminal region: FITC (ARP33062_P050-FITC)

• Gene Name:

  POU class 3 homeobox 3

• Gene Aliases:

  BRN1, OTF8, oct-8, SNIBFIS, brain-1

• Gene ID:

  5455

• Swiss Prot:

  P20264

• Accession Number:

  NP_006227

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human POU3F3

• Target:

  POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') .POU3F3 is a member of the class III POU family of transcription factors (see POU3F1; MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].

• Partner Proteins:

  Dlg4; SOX8; PPP1R15A; SOX10; SOX11; POU3F4

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  POU3F3 is supported by BioGPS gene expression data to be expressed in OVCAR3

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%; Mouse: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  50kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  500

• NCBI Gene Symbol:

  POU3F3

• Protein Name:

  POU domain, class 3, transcription factor 3

• Nucleotide Accession Number:

  NM_006236