Clonidine-d4

• Description :

  Clonidine-d4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an agonist of α2-adrenoceptor and potent antihypertensive agent[1][2][3][4][5].

• CAS Number :

  [62497-68-1]

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling; Others

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cardiovascular Disease; Endocrinology; Cancer

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC(C=CC=C1Cl)=C1NC2=NC([2H])([2H])C([2H])([2H])N2

• Molecular Formula :

  C9H5D4Cl2N3

• Molecular Weight :

  234.12

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Bugajski J, et al. The involvement of central alpha-adrenergic and histamine H2-receptors in the hypothermia induced by clonidine in the rat. Neuropharmacology. 1980 Jan;19 (1) :9-15.; Zhang YM, et al. Clonidine induces calcitonin gene-related peptide expres

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported