Clonidine-d4

CAT: 0804-HY-B0409S-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0409S-01Size:5 mg
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Description
Clonidine-d4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an agonist of α2-adrenoceptor and potent antihypertensive agent[1][2][3][4][5].
CAS Number
[62497-68-1]
UNSPSC
12352005
Target
Adrenergic Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology; Cancer
Solubility
10 mM in DMSO
Smiles
ClC(C=CC=C1Cl)=C1NC2=NC([2H])([2H])C([2H])([2H])N2
Molecular Formula
C9H5D4Cl2N3
Molecular Weight
234.12
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Bugajski J, et al. The involvement of central alpha-adrenergic and histamine H2-receptors in the hypothermia induced by clonidine in the rat. Neuropharmacology. 1980 Jan;19 (1) :9-15.; Zhang YM, et al. Clonidine induces calcitonin gene-related peptide expres
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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