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Tegoprazan

CAT: 1596-AR-T03383-03Size: 50 UnitsDry Ice: NoHazardous: No
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CAT#:1596-AR-T03383-03Size:50 Units
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CAS Number
942195-55-3
Synonyms
7-[[ (4S) -5,7-Difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N, N,2-trimethyl-1H-benzimidazole-5-carboxamide
Molecular Formula
C20H19F2N3O3
Molecular Weight
387.39
API Name
Tegoprazan

Chemical Information

Tegoprazan

Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related gastrointestinal diseases. This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB) with a fast onset of action and the ability to control gastric pH for a prolonged period of time. Tegoprazan’s strong and sustained effect is due to its ability to be slowly cleared from the gastric glands and exertion of effects independent of acid levels. It has also been observed to be efficacious independent of food intake.

CAS Number942195-55-3
PubChem CID23582846
IUPAC Name7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide
Molecular FormulaC20H19F2N3O3
Molecular Weight387.4
XLogP3.2
Topological Polar Surface Area67.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count28
Formal Charge0
Complexity581
SMILES
CC1=NC2=C(N1)C=C(C=C2O[C@H]3CCOC4=C3C(=CC(=C4)F)F)C(=O)N(C)C
InChI
InChI=1S/C20H19F2N3O3/c1-10-23-14-6-11(20(26)25(2)3)7-17(19(14)24-10)28-15-4-5-27-16-9-12(21)8-13(22)18(15)16/h6-9,15H,4-5H2,1-3H3,(H,23,24)/t15-/m0/s1
InChIKey
CLIQCDHNPDMGSL-HNNXBMFYSA-N
Chemical Structure
2D Structure
2D structure of Tegoprazan
CAS: 942195-55-3
CID: 23582846
Formula: C20H19F2N3O3
MW: 387.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight387.4
XLogP33.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass387.13944780
Monoisotopic Mass387.13944780
Topological Polar Surface Area67.5 Ų
Heavy Atom Count28
Formal Charge0
Complexity581
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
SMB19555-01Tegoprazan
RM-T051608-01Tegoprazan Impurity 8 ((R) -Tegoprazan)

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