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GC373

CAT: 0804-HY-160832Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-160832Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1429218-54-1
UNSPSC Description
GC373 is a potent inhibitor of SARS-CoV-2 Mpro that blocks virus replication with an IC50 of 0.4 μM. CG373 can be utilized in anti-COVID-19 research[1].
Target Antigen
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gc373.html
Smiles
O=C(OCC1=CC=CC=C1)N[C@@H](CC(C)C)C(N[C@H](C=O)C[C@H]2C(NCC2)=O)=O
Molecular Weight
403.47
References & Citations
[1]Vuong W, et al. Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies. Eur J Med Chem. 2021 Oct 15;222:113584.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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