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Allocryptopine

CAT: 0804-HY-N1933-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1933-01Size:5 mg
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Description
Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Macleaya cordata (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current[1][2].
CAS Number
485-91-6
UNSPSC
12352005
Hazard Statement
H302
Target
Potassium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/allocryptopine.html
Concentration
10mM
Purity
99.53
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C(C(CCN(C)CC2=C(OC)C(OC)=CC=C2C1)=C3)=CC4=C3OCO4
Molecular Formula
C21H23NO5
Molecular Weight
369.41
Precautions
H302
References & Citations
[1]Xu B, et al. Effect of α-Allocryptopine on Delayed Afterdepolarizations and Triggered Activities in Mice Cardiomyocytes Treated with Isoproterenol. Evid Based Complement Alternat Med. 2015;2015:634172.|[2]Lin K, et al. Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells. Acta Pharmacol Sin. 2013 Jun;34 (6) :847-58.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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