EcDsbB-IN-10

• Product Name Alternative:

  (±)-Norverapamil (hydrochloride); D591 (hydrochloride)

• UNSPSC Description:

  EcDsbB-IN-10 (compound 12) is an inhibitor of EcDsbB (E. coli DsbB) enzyme, with a Ki of 0.8 nM and an IC50 of 18.85 nM[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ecdsbb-in-10.html

• Purity:

  98.71

• Solubility:

  DMSO : 3 mg/mL (ultrasonic;warming)

• Smiles:

  O=C1C(Cl)=C(C=NN1CC2=CC=CC=C2Cl)Cl

• Molecular Weight:

  289.55

• References & Citations:

  [1]Landeta C, et al. Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Nat Chem Biol. 2015 Apr;11(4):292-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  112749-52-7