Recombinant Mouse/Rat TGF-beta 1
CAT:
855-EPT223
Size:
50 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No


Recombinant Mouse/Rat TGF-beta 1
Background:
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I) . Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.Description:
Recombinant Mouse/Rat Transforming Growth Factor Beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.Synonyms:
TGF-beta-1; TGFB; TGF-b1; TGFB1; CEDLAP;latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1UniProt:
P04202Accession Number:
P04202Endotoxin:
Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.Purity:
Greater than 95% as determined by reducing SDS-PAGE.Bioactivity:
Immobilized Mouse/Rat TGF-beta 1 (Cat#CK33) at 2μg/ml (100 μl/well) can bind Mouse TGFBR2-His (Cat#CM05) .The ED50 of Mouse TGFBR2-His (Cat#CM05) is 2.5 ug/ml.Reconstitution:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Molecular Weight:
12.8 KDaShipping Conditions:
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.Storage Conditions:
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.Notes:
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.Observed Molecular Weight:
13 KDa, reducing conditionsOther Product Names:
TGF-beta-1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1CAS Number:
9000-83-3