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Recombinant Human CFHR2 (C-6His)

CAT: 0855-EPT125Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0855-EPT125Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Complement Factor H-Related Protein 2 (CFHR2) is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 is synthesized as a 270 amino acid precursor that contains an 18 amino acid signal peptide and a 252 amino acid mature chain with 4 Sushi (CCP/SCR) domains. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.
Description
Recombinant Human Complement Factor H-Related 2 is produced by our Mammalian expression system and the target gene encoding Glu19-Lys270 is expressed with a 6His tag at the C-terminus.
UniProt
P36980
Accession Number
P36980
Endotoxin
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Molecular Weight
29.78 KDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Storage Temperature
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Notes
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Observed Molecular Weight
31&35 KDa, reducing conditions
Other Product Names
Complement Factor H-Related Protein 2; FHR-2; DDESK59; H Factor-Like 3; H Factor-Like Protein 2; CFHR2; CFHL2; FHR2; HFL3

UniProtKB · P36980

Complement factor H-related protein 2

FHR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P36980
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CFHR2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FHR-2
EC number
—
Processing
Precursor
Secondary accessions
Q14310, Q5T9T1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoprotein

Domain

RepeatSignalSushi

Cellular component

Secreted

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