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Recombinant Human CFHR4 (C-6His)

CAT: 0855-EPT117Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0855-EPT117Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Complement factor H-related protein 4 is a protein that in humans is encoded by the CFHR4 gene. It is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains. CFHR4 is synthesized as a 578 amino acid precursor that contains an 19 amino acid signal peptide and a 569 amino acid mature chain. Human CFHR4 is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.
Description
Recombinant Human Complement Factor H-related Protein 4 is produced by our Mammalian expression system and the target gene encoding Glu20-Glu578 is expressed with a 6His tag at the C-terminus.
UniProt
Q92496
Accession Number
Q92496
Endotoxin
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Molecular Weight
64.1 KDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Storage Temperature
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Notes
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Observed Molecular Weight
90-110 KDa, reducing conditions
Other Product Names
Complement factor H-related protein 4; FHR-4; CFHR4; CFHL4

UniProtKB · Q92496

Complement factor H-related protein 4

FHR4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92496
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CFHR4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FHR-4
EC number
—
Processing
Precursor
Secondary accessions
A8K9N7, B1ALQ9, C9J7J7, Q5DVJ7, Q9UJY6
Protein keywords

Coding sequence diversity

Alternative splicing

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

Domain

RepeatSignalSushi

Cellular component

Secreted

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