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Recombinant Mouse M-CSF (C-6His)

CAT: 0855-EPT050Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0855-EPT050Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Macrophage colony-stimulating factor 1 (M-csf) is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Description
Recombinant Mouse Macrophage Colony-stimulating Factor 1 is produced by our Mammalian expression system and the target gene encoding Lys33-Glu262 is expressed with a 6His tag at the C-terminus.
UniProt
P07141
Accession Number
P07141
Endotoxin
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Molecular Weight
27 KDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Storage Temperature
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Notes
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Observed Molecular Weight
37-56 KDa, reducing conditions
Other Product Names
Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm

UniProtKB · P07141

Macrophage colony-stimulating factor 1

CSF1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P07141
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Csf1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
CSF-1, MCSF
EC number
—
Processing
Precursor
Secondary accessions
Q3U395, Q8R3C8
Protein keywords

Technical term

3D-structureDirect protein sequencingReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

Molecular function

CytokineGrowth factor

PTM

Disulfide bondGlycoproteinProteoglycan

Biological process

ImmunityInflammatory responseInnate immunity

Domain

SignalTransmembraneTransmembrane helix

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