HSD17B13-IN-55

• UNSPSC Description:

  HSD17B13-IN-55 (Compound 167) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-55 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].

• Target Antigen:

  17β-HSD

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/hsd17b13-in-55.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=C(Cl)C=C(C(NC2=CC=C(C)C(N=C(C(F)F)N3CC4=CC=CC=C4C(F)(F)F)=C2C3=O)=O)C=C1Cl

• Molecular Weight:

  572.31

• References & Citations:

  [1]Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2770247-58-8