Cinchonine (monohydrochloride hydrate)

Cinchonine (monohydrochloride hydrate)

• CAS Number: 206986-88-1
• UNSPSC Description: Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis[1].
• Target Antigen: Apoptosis; Parasite
• Type: Natural Products
• Related Pathways: Anti-infection;Apoptosis
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer; Infection; Metabolic Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/cinchonine-monohydrochloride-hydrate.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H](C1=CC=NC2=CC=CC=C12)[C@]3([H])[N@@]4C[C@H](C=C)[C@@H](CC4)C3.[H]Cl.[x].O
• References & Citations: [1]Jin ZL, et, al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported