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Midodrine

CAT: 0804-HY-12749-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12749-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Midodrine is a selective and orally active adrenergic α1-receptor agonist. Midodrine can strengthen vascular contraction. Midodrine can be used for the researches of cardiovascular disease, such as orthostatic hypotension[1][2][3].
CAS Number
42794-76-3
Product Name Alternative
(±) -Midodrin
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Midodrine.html
Purity
99.67
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NCC(C1=CC(OC)=CC=C1OC)O)CN
Molecular Formula
C12H18N2O4
Molecular Weight
254.28
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Criscuoli M, et al. Catecholamines released from the adrenal medulla exert a compensatory, protective effect at beta 2-adrenoceptors against Paf-induced death in mice. Br J Pharmacol. 1988 Jan;93 (1) :132-8.|[2]Inchan A, et al. Anti-hypotensive effect of "Yahom Navakot" in rats with orthostatic hypotension. J Tradit Complement Med. 2021 Aug 3;12 (2) :180-189.|[3]Lee YJ, et al. Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ. PPAR Res. 2020 Feb 1;2020:3785137.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor

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