Midodrine hydrochloride

CAT: 0931-MF-0013400-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0013400-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3092-17-9
Target
Adrenergic Receptor
Related Pathways
Neuroscience|||GPCR/G Protein
Purity
>99.99%
Bioactivity
Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier and is therefore not associated with effects on the central nervous system. Midodrine hydrochloride (Pro-Amatine) is the hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties.
Smiles
Cl.COc1cc(C(O)CNC(=O)CN)c(OC)cc1
Molecular Formula
C12H19ClN2O4
Molecular Weight
290.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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