Fluconazole (Standard)

• UNSPSC Description:

  Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL[1].

• Target Antigen:

  Antibiotic; Bacterial; Fungal

• Type:

  Reference Standards

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/fluconazole-standard.html

• Smiles:

  FC1=CC=C(C(O)(CN2C=NC=N2)CN3C=NC=N3)C(F)=C1

• Molecular Weight:

  306.27

• References & Citations:

  [1]H Yamaguchi, et al. [In vitro activity of fluconazole, a novel bistriazole antifungal agent]. Jpn J Antibiot. 1989 Jan;42(1):1-16.|[2]M A Pfaller, et al. Interpretive breakpoints for fluconazole and Candida revisited: a blueprint for the future of antifungal susceptibility testing. Clin Microbiol Rev. 2006 Apr;19(2):435-47.|[3]P G Sohnle, et al. Effect of fluconazole on viability of Candida albicans over extended periods of time. Antimicrob Agents Chemother. 1996 Nov;40(11):2622-5.|[4]A Louie, et al. Pharmacodynamics of fluconazole in a murine model of systemic candidiasis. Antimicrob Agents Chemother. 1998 May;42(5):1105-9.

• Shipping Conditions:

  Room temperature

• CAS Number:

  86386-73-4