SU-4313

• UNSPSC Description:

  SU-4313 is a potent protein tyrosine kinases (PTKs) modulator with IC50s of 14.5 μM, 18.8 μM, 11 μM, 16.9 μM, 8.0 μM for PDGFR, FLK-1, EGFR, HER2 Kinase and IGF-1R, respectively. SU-4313 has the potential for modulating tyrosine kinase signal transduction in order to regulate abnormal cell proliferation[1].

• Target Antigen:

  EGFR; IGF-1R; PDGFR

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/su-4313.html

• Smiles:

  O=C1NC2=C(/C1=C/C3=CC=C(C(C)C)C=C3)C=CC=C2

• Molecular Weight:

  263.33

• References & Citations:

  [1]Peng Cho Tang, et al. Indolinone compounds for the treatment of disease. WO1996040116A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  186611-55-2