Phenylpiracetam

CAT: 0804-HY-14840-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-14840-01Size:5 mg

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Description

Phenylpiracetam (Phenotropyl; Phenotropil) is a phenylated derivative of the nootropic drug piracetam. It is used as a stimulant nootropic drug that can be up to 30-60 times more potent than piracetam. IC50 Value: Target: AMPA receptor allosteric modulator in vitro: N/A in vivo: In the open-field test, a significant increase in locomotor activity was observed after a single administration of R-phenotropil at doses of 10 and 50 mg/kg and S-phenotropil at a dose of 50 mg/kg. In the forced swim test, R-phenotropil induced an antidepressant effect at doses of 100 and 50 mg/kg, and S-phenotropil was active at a dose of 100 mg/kg. R-phenotropil significantly enhanced memory function in a passive avoidance response test at a dose of 1 mg/kg; the S-enantiomer did not show any activity in this test [1].

CAS Number

77472-70-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/phenylpiracetam.html

Purity

99.91

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N)CN1C(CC(C2=CC=CC=C2)C1)=O

Molecular Formula

C12H14N2O2

Molecular Weight

218.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Zvejniece L, et al. Investigation into stereoselective pharmacological activity of phenotropil. Basic Clin Pharmacol Toxicol. 2011 Nov;109 (5) :407-12.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

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