Products for Research Use Only
RegisterLogin

Teglarinad (chloride)

CAT: 0804-HY-10080-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-10080-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Teglarinad chloride (GMX1777) is a proagent of GMX1778 (a nicotinamide phosphoribosyl transferase inhibitor) . Teglarinad chloride exhibits antitumor activity in mice can be attributed to inhibition of NAMPT. Teglarinad chloride also enhances radiation efficacy, mediated by interference with DNA repair and antiangiogenesis[1][2].
CAS Number
432037-57-5
Product Name Alternative
GMX1777; EB-1627
UNSPSC
12352005
Target
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/teglarinad-chloride.html
Purity
99.67
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
N#CN/C(NC1=CC=[N+](C=C1)COC(OCCOCCOCCOCCOC)=O)=N/CCCCCCOC2=CC=C(C=C2)Cl.[Cl-]
Molecular Formula
C30H43Cl2N5O8
Molecular Weight
672.60
References & Citations
[1]Kato H, et, al. Efficacy of combining GMX1777 with radiation therapy for human head and neck carcinoma. Clin Cancer Res. 2010 Feb 1;16 (3) :898-911.|[2]Beauparlant P, et, al. Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777. Anticancer Drugs. 2009 Jun;20 (5) :346-54.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1

Related Products

CatalogName
HY-W012954S-01TMA chloride-d12 (chloride)
HY-N8262Dehydrocorybulbine (chloride)
HY-N0926A-01Columbamine (chloride)
HY-B0567-01Dequalinium (Chloride)
HY-W012412-01Tetrapropylammonium (chloride)
HY-W011087-01Benzyldimethyltetradecylammonium (chloride)
HY-B1793-01Tetraethylammonium (chloride)
HY-100978-01(±) -Hexanoylcarnitine (chloride)
HY-103314-01Gadolinium chloride
HY-B1208Carbamoylcholine (chloride)

Alternative Products

CatalogName
BUP21765Teglarinad chloride
A12669-50Teglarinad chloride 50mg
A12669-25Teglarinad chloride 25mg
A12669-10Teglarinad chloride 10mg
A12669-5Teglarinad chloride 5mg
A12669-100Teglarinad chloride 100mg
A12669-1Teglarinad chloride 1mg
189775-01Phenyl Methanesulphonyl Chloride (α-Toluenesulphonyl Chloride; Phenylmethylsulphonyl Chloride)
3125490Tin chloride (stannous chloride)
3121645Cobalt chloride (Cobaltous chloride)

Popular Products