(±) -Hexanoylcarnitine (chloride)

• Description :

  (±) -Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±) -Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways[1][2].

• Product Name Alternative :

  DL-Hexanoylcarnitine (chloride)

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H317

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/racemic-hexanoylcarnitine-chloride.html

• Purity :

  98.0

• Solubility :

  H2O : 250 mg/mL (ultrasonic)

• Smiles :

  CCCCCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]

• Molecular Formula :

  C13H26ClNO4

• Molecular Weight :

  295.80

• Precautions :

  H302, H317

• References & Citations :

  [1]Scarale MG, et al. Circulating Metabolites Associate With and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes. Diabetes. 2022 Jun 1;71 (6) :1363-1370. |[2]Obayashi H, et al. Plasma 2-hydroxyglutarate and hexanoylcarnitine levels are potential biomarkers for skeletal muscle toxicity in male Fischer 344 rats. J Toxicol Sci. 2017;42 (4) :385-396.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [6920-35-0]