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(±) -Hexanoylcarnitine (chloride)

CAT: 0804-HY-100978-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100978-01Size:5 mg
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Description
(±) -Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±) -Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways[1][2].
CAS Number
6920-35-0
Product Name Alternative
DL-Hexanoylcarnitine (chloride)
UNSPSC
12352211
Hazard Statement
H302, H317
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/racemic-hexanoylcarnitine-chloride.html
Purity
98.0
Solubility
H2O : 250 mg/mL (ultrasonic)
Smiles
CCCCCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]
Molecular Formula
C13H26ClNO4
Molecular Weight
295.80
Precautions
H302, H317
References & Citations
[1]Scarale MG, et al. Circulating Metabolites Associate With and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes. Diabetes. 2022 Jun 1;71 (6) :1363-1370. |[2]Obayashi H, et al. Plasma 2-hydroxyglutarate and hexanoylcarnitine levels are potential biomarkers for skeletal muscle toxicity in male Fischer 344 rats. J Toxicol Sci. 2017;42 (4) :385-396.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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