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Active Complement Factor B (CFB)

CAT: 0338-TRV-033186-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-033186-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
CF-B; BF; BFD; CFAB; GBG; H2-Bf; PBF2; B-Factor; Properdin; Properdin factor B; C3/C5 convertase; Glycine-rich beta glycoprotein
Synonyms
Complement Factor B
UniProt
P00751
Host
E. coli
Tag
N-terminal His and GST Tag
Applications
Cell culture; Activity Assays.
Field of Research
Infection immunity; Immune molecule; Hematology; Autoimmunity
Purity
> 90%
Form
Freeze-dried powder
Buffer
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Calculated Molecular Weight
44.3kDa
Observed Molecular Weight
44kDa
Fragment
Gly35~Asn160
Isoelectric Point
6.7
Product Name Synonym
Complement Factor B
Host or Source
E.coli
Organism Species
Homo sapiens (Human)

UniProtKB · P00751

Complement factor B

CFAB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00751
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CFB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.47
Processing
Precursor
Secondary accessions
B0QZQ6, O15006, Q29944, Q53F89, Q5JP67, Q5ST50, Q96HX6, Q9BTF5, Q9BX92
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Age-related macular degenerationDisease variantHemolytic uremic syndrome

Coding sequence diversity

Alternative splicing

PTM

Cleavage on pair of basic residuesDisulfide bondGlycationGlycoproteinZymogen

Biological process

Complement alternate pathwayImmunityInnate immunity

Molecular function

HydrolaseProteaseSerine protease

Domain

RepeatSignalSushi

Cellular component

Secreted

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