Recombinant Complement Factor B (CFB)

CAT: 0338-TRV-034646-01Size: 10 µgDry Ice: NoHazardous: No

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CAT#:0338-TRV-034646-01Size:10 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

9000-83-3

Product Name Alternative

CF-B; BF; BFD; CFAB; GBG; H2-Bf; PBF2; B-Factor; Properdin; Properdin factor B; C3/C5 convertase; Glycine-rich beta glycoprotein

Synonyms

Complement Factor B

UniProt

P00751

Expression System

Prokaryotic expression

Host

E. coli

Tag

N-terminal His Tag

Source

Prokaryotic expression

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

Field of Research

Infection immunity; Immune molecule; Hematology; Autoimmunity

Endotoxin

<1.0EU per 1μg (determined by the LAL method)

Purity

> 90%

Form

Freeze-dried powder

Buffer

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Calculated Molecular Weight

15.4 KDa

Observed Molecular Weight

16kDa

Fragment

Leu477~Thr600

Isoelectric Point

8.3

Subcellular Location

Secreted

Product Name Synonym

Complement Factor B

Host or Source

E.coli

Organism Species

Homo sapiens (Human)

UniProtKB · P00751

Complement factor B

CFAB_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P00751
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CFB
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.4.21.47
Processing: Precursor
Secondary accessions: B0QZQ6, O15006, Q29944, Q53F89, Q5JP67, Q5ST50, Q96HX6, Q9BTF5, Q9BX92

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Age-related macular degenerationDisease variantHemolytic uremic syndrome

Coding sequence diversity

Alternative splicing

PTM

Cleavage on pair of basic residuesDisulfide bondGlycationGlycoproteinZymogen

Biological process

Complement alternate pathwayImmunityInnate immunity

Molecular function

HydrolaseProteaseSerine protease

Domain

RepeatSignalSushi

Cellular component