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Active Tissue Plasminogen Activator (tPA)

CAT: 0338-TRV-035635-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-035635-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
PLAT; T-PA; t-plasminogen activator; Alteplase; Reteplase
Synonyms
Tissue Plasminogen Activator
UniProt
P11214
Host
E. coli
Tag
N-terminal His Tag
Applications
Cell culture; Activity Assays.
Field of Research
Metabolic pathway; Hematology
Purity
> 95%
Form
Freeze-dried powder
Buffer
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Calculated Molecular Weight
20.7kDa
Observed Molecular Weight
22kDa
Fragment
Glu359~Leu532
Isoelectric Point
5.5
Product Name Synonym
Tissue Plasminogen Activator
Host or Source
E.coli
Organism Species
Mus musculus (Mouse)

UniProtKB · P11214

Tissue-type plasminogen activator

TPA_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P11214
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Plat
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
t-PA, t-plasminogen activator, tPA
EC number
3.4.21.68
Processing
Precursor
Secondary accessions
Q6P7U0, Q91VP2
Protein keywords

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinZymogen

Technical term

Direct protein sequencingReference proteome

Domain

EGF-like domainKringleRepeatSignal

Molecular function

HydrolaseProteaseSerine protease

Biological process

Plasminogen activation

Cellular component

Secreted

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